Drug Name
Ilosone

Drug Uses
Ilosone is used for treating infections caused by certain bacteria. It is also used to prevent bacterial endocarditis and attacks of rheumatic fever. It may also be used for other conditions as determined by your doctor.

How to use
Use Ilosone as directed by your doctor. Check the label on the medicine for exact dosing instructions. Check the label on the medicine for exact dosing instructions.

• Take Ilosone by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.
• Swallow Ilosone whole. Do not break, crush, or chew before swallowing.
• Do not eat grapefruit or drink grapefruit juice while you use Ilosone .
• Ilosone works best if taken at the same times each day.
• To clear up your infection completely, take Ilosone for the full course of treatment. Keep taking it even if you feel better in a few days.
• If you miss a dose of Ilosone , take it as soon as possible. If it is almost time for the next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Drug Class and Mechanism
Ilosone is a macrolide antibiotic. It works by slowing the growth of, or sometimes killing, sensitive bacteria by reducing the production of important proteins needed by the bacteria to survive.

Missed Dose
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.

Storage
Store this medicine at room temperature in a tightly-closed container, away from heat and light.

Warnings/Precautions
Do NOT use Ilosone if:

• you are allergic to any ingredient in Ilosone
• you are taking astemizole, cisapride, conivaptan, diltiazem, dofetilide, an ergot alkaloid (eg, dihydroergotamine, ergotamine), everolimus, an HIV protease inhibitor (eg, ritonavir), an imidazole (eg, ketoconazole), nilotinib, pimozide, a QT-prolonging agent (eg, quinidine, sotalol), a quinolone (eg, ciprofloxacin), a streptogramin (eg, quinupristin/dalfopristin), terfenadine, or verapamil

Contact your doctor or health care provider right away if any of these apply to you.

Before using Ilosone:
Some medical conditions may interact with Ilosone . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have diarrhea or a stomach or intestinal infection
• if you have a history of kidney or liver disease, heart problems, a fast or irregular heartbeat, myasthenia gravis, or the blood disease porphyria

Some MEDICINES MAY INTERACT with Ilosone . Tell your health care provider if you are taking any other medicines, especially any of the following:

• Astemizole, cisapride, diltiazem, dofetilide, an HIV protease inhibitor (eg, ritonavir), imidazoles (eg, ketoconazole), nilotinib, pimozide, a QT-prolonging agent (eg, quinidine, sotalol), a quinolone (eg, ciprofloxacin), a streptogramin (eg, quinupristin/dalfopristin), terfenadine, or verapamil because side effects, such as heart toxicity or irregular heartbeat, may occur. Check with your doctor if you have questions about which medicines may affect your heartbeat.
• Conivaptan, ergot alkaloids (eg, dihydroergotamine, ergotamine), or everolimus because the risk of their side effects may be increased by Ilosone
• Many prescription and nonprescription medicines (eg, used for aches and pains, allergies, blood thinning, breathing problems, cancer, diabetes, erection problems, gout, heart problems, high blood calcium levels, high blood pressure, high cholesterol, HIV infection, inflammation, infections, low blood sodium levels, migraine, mood or mental problems, overactive bladder, Parkinson disease, prevention of organ transplant rejection, seizures, stomach problems, trouble sleeping), multivitamin products, and herbal or dietary supplements (eg, herbal teas, coenzyme Q10, garlic, ginseng, ginkgo, St. John's wort) may also interact with Ilosone . Ask your doctor or pharmacist if you are unsure if any of your medicines might interfere with Ilosone .

Possible Side Effects
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Diarrhea; loss of appetite; nausea; stomach pain; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); bloody stools; decreased hearing or hearing loss; irregular heartbeat; muscle weakness; red, swollen, blistered, or peeling skin; seizures; severe diarrhea; severe stomach pain or cramps; symptoms of liver problems (eg, yellowing of the skin or eyes, pale stools, severe or persistent nausea, vomiting, loss of appetite, or dark urine).

More Information
If you have any questions about Ilosone , please talk with your doctor, pharmacist, or other health care provider.
Ilosone is to be used only by the patient for whom it is prescribed. Do not share it with other people.
If your symptoms do not improve or if they become worse, check with your doctor.